De Lange Syndrome

De Lange Syndrome is a relatively common syndrome with multiple congenital birth defects and developmental delays with features that include an abnormally small head (microcephaly), hair low on the nape of the neck, low-set ears, hair well down onto the forehead, bushy eyebrows, eyebrows that meet in the middle (synophrys), unusually long eyelashes, depressed bridge of the nose, up tilted tip of the nose, forward-directed nostrils, protuberance of the upper jaw (maxillary prognathism), and small, widely spaced teeth.

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